You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air

https://marcosgnc317.clearhavendigest.com/posts/why-you-should-never-vacuum-rodent-droppings-in-your-attic

You should never vacuum rodent droppings in your attic because vacuuming can send contaminated particles into the air and raise the risk of exposure to rodent-borne diseases.